肝臟移植

March 23, 1984
The first liver transplantation in Taiwan was performed by Dr. Chao-Long Chen at Linkou Chang Gung Memorial Hospital. It was the first successful liver transplant with extended survival in Asia as well as the first case where the organ was procured from a brain dead donor. This event ignited extensive debate and discussion that led to a consensus on the definition of brain death in the medical profession.

October 19, 1984
The Medical Association of the Republic of China issued the statement that “brain death equals death”, which prompted the legislation of the Human Organ Transplant Act. The concept of brain death was then legally defined and accepted.　

November 4, 1985
Dr. Chao-Long Chen performed the second case of liver transplantation in Linkou. The patient is alive to date. Since the first liver transplant patient died from a traffic accident three years after transplantation, the second case became the longest surviving liver transplant recipient in Asia.

World transplant records. In: Cecka JM, Terasaki PI, eds. Clinical transplants 2001.

1987
Dr. Chao-Long Chen won the honor of outstanding medical staff in the Chang Gung System for three times because of his contribution in liver transplantation. The Gold Medals were from the Formosa Plastic Group Chairman, Yung-Ching Wang (1987, 1991, 1996)

August, 1988 – July, 1989
Dr. Hideo Kawarasaki of the University of Tokyo led his liver transplant team to Taiwan to collaborate with Dr. Chao-Long Chen for six visits. They cooperated in developing an animal model of living donor liver transplantation.

June 19, 1990
Professor Masatoshi Makuuchi invited Dr. Chao-Long Chen to supervise their first liver transplant operation in National Shinshu University. The recipient became the longest surviving liver transplant patient in Japan.　

August 10, 1990
Dr. Chao-Long Chen performed the first case of liver transplantation for biliary atresia in Taiwan at Keelung Chang Gung Memorial Hospital. The patient is alive and well to date. It was the first successful pediatric liver transplant in Taiwan.　

August 28, 1991
Dr. Chao-Long Chen performed the first case of liver transplantation for choledochal cyst. The patient is alive and well to date.

June 12, 1992
Dr. Chao-Long Chen won the most outstanding alumnus award from Kaohsiung Medical University.

December 18, 1992
Dr. Chao-Long Chen won the first prize of outstanding scientific papers of the year 1992 from the International College of Surgeons, China Section with his essay “Liver Transplantation in Taiwan: The Chang Gung Experience”.

January 15, 1994
The first liver transplantation for hepatitis C in Taiwan was performed at the Kaohsiung Chang Gung Memorial Hospital. The recipient delivered a healthy baby three years later, becoming the first liver transplant recipient to become a mother after the operation.　

June 17, 1994
The Liver Transplant Program of the Kaohsiung Chang Gung Memorial Hospital (KCGMH-LTP) performed the first living donor liver transplantation in Taiwan.　

World transplant records. In: Cecka JM, Terasaki PI, eds. Clinical transplants 2001. UCLA Immunogenetic Center, 2002:297

October 7, 1994
Dr. Chao-Long Chen won the first prize of outstanding scientific papers of the year 1994 from the International College of Surgeons, China Section, with his essay “Metabolic Effects of Liver Transplantation in Wilson’s Disease”.　

December 1994
Dr. Chao-Long Chen was invited as a Visiting Professor of Surgery by the University of Miami, U.S.A.

January 6-7, 1996
Kaohsiung Chang Gung Memorial Hospital hosted the “First International Living Donor Liver Transplantation Symposium”.

January 18, 1996
Dr. Chao-Long Chen obtained the National Outstanding Award in Science and Technology from the Executive Yuan of Taiwan.　

March 13, 1996
The KCGMH-LTP performed the first liver transplantation for glycogen storage disease in Taiwan and the patient is alive and well to date.

April 12, 1996
Six members of KCGMH-LTP: Chao-Long Chen, Yaw-Sen Chen, Yu-Fan Cheng, Yuan-Cheng Chiang, Fu-Liu Hsing and Miao-Wei Huang, were invited by the National Kidney and Transplant Institute in Manila to performed the first living donor liver transplantation in the Philippines.

November 6, 1996
The KCGMH-LTP performed the first liver transplantation for Budd-Chiari syndrome in Taiwan. The patient got married and had children after transplantation.　

May 20, 1997
The KCGMH-LTP performed the first split liver transplantation in Asia.

Chen CL, et al. Split liver transplantation (Review article) Asian Journal of Surgery 25:285-290, 2002

July 1, 1997
The KCGMH-LTP integrated the basic and clinical research and founded the liver transplant research center. Associate Professor Shigeru Goto was in charge of the basic arm, which currently consists of transplant cellular immunology lab, transplant molecular biology lab, transplant protein chemistry lab, transplant surgery lab, SPF animal lab and bioartificial liver lab.

October 8, 1997
The KCGMH-LTP performed the first living donor liver transplant without transfusion of blood or blood products.

World transplant records. In: Cecka JM, Terasaki PI, eds. Clinical transplants 2001.

October 1997
Dr. Chao-Long Chen was appointed as an Honorary Professor by the China Medical University in Shengyang, China.

January 21, 1998
The KCGMH-LTP performed liver transplantation for a Japanese child named Hirotasu Kushita, who was the first foreign patient to undergo liver transplantation in Taiwan.

April 1, 1998
The KCGMH-LTP began to train Japanese and Southeast Asian surgical fellows, including:

            Toshiro Tatsuma                  (1998.4-1993.3)
            Vanessa H. de Villa             (1998.7-2002.7)
            Hirotaka Yokoyama             (1999.4-2000.3)
            Yukio Iwashita                      (2000.4.-2001.3)
            Mitsuhisa Takatsuki             (2001.6-2003.3)

November 1998
Dr. Chao-Long Chen was appointed as Visiting Professor by the Third Military Medical University of China.

January 14, 1999
The KCGMH-LTP performed the first adult-to-adult right lobe living donor liver transplantation in Taiwan and the patient is alive and well to date.

January 27, 1999
The KCGMH-LTP performed the first internationally collaborated split liver transplantation in Asia in cooperation with the University of Hong Kong.

October 1999
Seigo Kitano, Professor of Surgery at Oita Medical University of Japan, visited Kaohsiung Chang Gung Memorial Hospital to observe living donor liver transplantation.

November 1999
Dr. Chao-Long Chen was appointed as Visiting Professor by Beijing Friendship Hospital of the China Capital Medical University.

November 24, 1999
The KCGMH-LTP performed the first liver transplantation for neonatal hepatitis in Taiwan. The patient is alive and well to date.

January 21, 2000
Taiwan’s first case of spousal living donor liver transplantation was performed at Kaohsiung Chang Gung Memorial Hospital.

April 8, 2000
In Kaohsiung Chang Gung Memorial Hospital, Drs. Chao-Long Chen, Yaw-Sen Chen and Chih-Chi Wang accomplished three separate liver transplants simultaneously. All three patients were discharged from the hospital on May 8. They have been alive and well to date.

June 28, 2000
The KCGMH-LTP performed the first liver transplantation for Alagille syndrome in Taiwan. The patient is alive and well to date.

November 1, 2000
The KCGMH-LTP performed its 100^th liver transplant. Of these, 52 were living donor liver transplants and the survival rate was 100%, which is the highest global record. Since 2000, living donor liver transplantation has become a routine operation, being performed at Kaohsiung Chang Gung Memorial Hospital on a weekly basis.

December 2000
Surgeons from Kyushu University, Mitsuo Shimada, Takashi Nishizaki and Yuji Soejima visited Kaohsiung Chang Gung Memorial Hospital to observe living donor liver transplantation.

February 21, 2001
Jose Gabrielle Teotico from the Philippines underwent live donor liver transplantation in Kaohsiung Chang Gung Memorial Hospital. He was the first foreign patient to undergo living donor liver transplantation in Taiwan.

April 25, 2001
The KCGMH-LTP performed the first living donor liver transplantation with a liver graft from a pregnant woman for her daughter in a life threatening situation. After five months, the mother delivered a healthy baby.

World transplant records. In: Cecka JM, Terasaki PI, eds. Clinical transplants 2001. UCLA Immunogenetic Center, 2002:297

May 30, 2001
A South African Chinese underwent living donor liver transplantation in Kaohsiung Chang Gung Memorial Hospital. He was the first patient from another continent to undergo liver transplantation in Taiwan.

October 2001
Dr. Chao-Long Chen was appointed as Visiting Professor by Nankai University of Tianjin, China

October 2001
Professor K.C. Tan of National University of Singapore led the liver transplant team consisting of ten members to observe living donor liver transplants in Kaohsiung Chang Gung Memorial Hospital

November 12, 2001
The liver transplantation team of Kaohsiung Chang Gung Memorial Hospital consisting of Chao-Long Chen, Yaw-Sen Chen, Chih-Chi Wang, Vanessa H. de Villa, Yuan-Cheng Chiang, Tsan-Shiun Lin, Yu-Fan Cheng, Tung-Liang Huang, Bruno Jawan, Jien-Wei Liu, Miao-Wei Huang, Yuan-Yuan Wang, Li-Man Lin and Hsiu-Lan Liao, altogether fourteen staff members, were invited by Peking University to perform the first pediatric right lobe living donor liver transplant in China. This is the joint medical adventure of the largest scale so far between the two sides of the Taiwan Strait.

December 2001
Dr. Chao-Long Chen won the first prize of outstanding scientific papers of the year 2001 from the International College of Surgeons, Taiwan Section, with his paper entitled “Minimal Blood Loss Living Donor Hepatectomy”.

January 31, 2002
The liver transplantation team of Kaohsiung Chang Gung Memorial Hospital consisting of thirteen staff members including Chao-Long Chen, Yaw-Sen Chen, Chih-Chi Wang, Chih-Che Lin, Yuan-Cheng Chiang, Tsan-Shiun Lin, Yu-Fan Cheng, Tung-Liang Huang, Bruno Jawan, Hsiang-Ning Luk, Miao-Wei Huang, Chiung-Chuan Tsai and Li-Man Lin, were invited by the Peking Union Medical College Hospital to team up with Jie-Fu Huang and Shou-Xian Zhong to perform the first adult-to-adult living donor liver transplantation in Beijing.

February 2002
Dr. Chao-Long Chen was appointed as Visiting Professor by the Peking Union Medical College Hospital of the Chinese Academy of Medical Sciences.

April 10, 2002
The KCGMH-LTP performed its 100^th living donor liver transplant. The 5-year actuarial patient and graft survival rates of the first 100 recipients were both at 97%.

April 20, 2002
Kaohsiung Chang Gung Memorial Hospital hosted the 2002 Living Donor Liver Transplantation Symposium. The major speakers were Professor Koichi Tanaka of Kyoto University, Professor Masatoshi Makuuchi of University of Tokyo, Professor Sung-Gyu Lee of Ulsan University, Professor Sheung-Tat Fan of University of Hong Kong and Professor Chao-Long Chen of Chang Gung University.

August 28, 2002
The KCGMH-LTP performed the first dual graft living donor liver transplantation in Taiwan.

Living-Donor Liver Transplantation: The Asian Perspective was published as a Supplement to Transplantation.

Professor Chao-Long Chen was appointed as the Superintendent of the Chang Gung Memorial Hospital, Kaohsiung Medical Center.

Professor Chao-Long Chen and Professor Jatin P. Shah from Memorial Sloan- Kettering Cancer Center were conferred the title of Honory Fellow by the Philippine College of Surgeons.

October 1, 2003
The KCGMH-LTP performed its 150th living donor liver transplant. All donors are alive and back to their pre-donation life styles. The actuarial survival rates of the 150 recipients are 97.9% at one year and 96% at five years.

October 24, 2003
Dr. Chao-Long Chen won the first prize of outstanding scientific papers of the year 2003 from the International College of Surgeons, Taiwan Section, with his essay “Living Donor Liver Transplantation: 12 Years of Experience in Asia”

Eduardo Fernandes (2004-2005)

January 2005
Professor Chao-Long Chen became member of the Editorial Board of the Journal " LIVER TRANSPLANTATION"
(SCI impact factor 3.984)

July 2005
Dr. Yu-Fan Cheng was awarded a travel grant from the 11th Annual Congress of the International Liver Transplantation Society in Los Angeles, USA to present his paper entitled "Hepatocellular carcinoma in liver transplantation".

October 26, 2005

The KCGMH-LTP performed the first split liver transplantation from a pediatric donor. Both recipients are alive and well.

Liver Transplantation Center of Chang Gung Memorial Hospital was awarded the "2005 Symbol of National Quality" and "Golden Award of 2005 National Biotechnology and Medical Care Quality Award".

Dr. Chih-Che Lin was awarded a travel grant from the 12th Annual Congress of the International Liver Transplantation Society in Milan, Italy to present his paper entitled "High level active immunization is a feasible and effective strategy to prevent de novo hepatitis B virus infection in pediatric patients after living donor liver transplantation"